Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.84 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.84 |
| ▸ | MMP9 | P14780 | 2/20 | 0.84 |
| ▸ | MMP3 | P08254 | 1/20 | 0.84 |
| ▸ | MMP7 | P09237 | 1/20 | 0.84 |
| ▸ | MMP10 | P09238 | 1/20 | 0.84 |
| ▸ | MMP8 | P22894 | 1/20 | 0.84 |
| ▸ | MMP12 | P39900 | 1/20 | 0.84 |
| ▸ | MMP13 | P45452 | 1/20 | 0.84 |
| ▸ | MMP14 | P50281 | 1/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5897954 | 1.00 | MMP2 (0.84) | MMP2ADAM17MMP9MMP3MMP7 | |
| Trifluoroacetic Acid SCHEMBL5897820 | 0.96 | MMP2 (0.78) | MMP2ADAM17MMP9MMP3MMP7 | |
| SCHEMBL5898489 | 0.92 | MMP2 (1.00) | MMP2ADAM17MMP9MMP3MMP7 | |
| SCHEMBL6791356 | 0.90 | ADAM17 (1.00) | MMP2ADAM17MMP9MMP3MMP7 | |
| SCHEMBL5898157 | 0.88 | MMP2 (0.82) | MMP2ADAM17MMP9MMP3MMP7 | |
| SCHEMBL5898186 | 0.88 | MMP2 (0.81) | MMP2ADAM17MMP9MMP3MMP7 | |
| Trifluoroacetic Acid SCHEMBL5898080 | 0.88 | MMP2 (0.91) | MMP2ADAM17MMP9MMP3MMP7 | |
| SCHEMBL5898448 | 0.87 | MMP2 (0.82) | MMP2ADAM17MMP9MMP3MMP7 | |
| SCHEMBL5898220 | 0.87 | MMP2 (0.80) | MMP2ADAM17MMP9MMP3MMP7 | |
| SCHEMBL5897706 | 0.87 | MMP2 (0.80) | MMP2ADAM17MMP9MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060212-A1 | ANTI-INFLAMMATORY COATING FOR IMPLANTABLE MEDICAL DEVICES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-07-22 | — | — | WO | claimed |