SCHEMBL6682369

SCHEMBL6682369

CCCCCCCCCCCCCCCCC(C(=O)O)(C(=O)O)C(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ALDH1A1 P00352 4/20 0.40
ESR1 P03372 1/20 0.38
ALOX5 P09917 3/20 0.38
NPC1 O15118 1/20 0.37
MGLL Q99685 1/20 0.37
GAA P10253 3/20 0.36
MAPT P10636 2/20 0.36
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
HCAR3 P49019 1/20 0.36
PKM P14618 1/20 0.36
RAB9A P51151 1/20 0.36
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Myristyl Alcohol SCHEMBL29023767 0.74 GAA (0.49) CYP3A4SMN1; SMN2ALDH1A1ESR1ALOX5
Dinitrophenylene SCHEMBL27643529 0.73 ALDH1A1 (0.47) CYP3A4SMN1; SMN2ALDH1A1GAAMAPT
SCHEMBL3072804 0.73 HTT (0.55) SMN1; SMN2ALDH1A1ALOX5GAAMAPT
SCHEMBL9678186 0.70 ESR1 (0.71) ALDH1A1ESR1NPC1MAPTRAB9A
SCHEMBL9679699 0.70 ESR1 (0.71) ALDH1A1ESR1NPC1MAPTRAB9A
SCHEMBL11700483 0.70 ESR1 (0.71) ALDH1A1ESR1NPC1MAPTRAB9A
SCHEMBL9678194 0.70 ESR1 (0.71) ALDH1A1ESR1NPC1MAPTRAB9A
SCHEMBL9733961 0.70 PKM (0.64) ALDH1A1MGLLGAAMAPTHDAC3
SCHEMBL9735264 0.70 CYP3A4 (0.51) CYP3A4SMN1; SMN2ALDH1A1ALOX5NPC1
SCHEMBL9734781 0.70 PKM (0.64) ALDH1A1MGLLGAAMAPTHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004067623-A2 POLYMIDE RESIN FOR NON-RUBBING VERTICAL ALIGNMENT MATERIALS AND PREPARATION METHOD THEREOF KIM YONG-BAE (KR) 2004-08-12 WO disclosed