Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4615822 | 1.00 | — | — | |
| SCHEMBL9307288 | 1.00 | DNM1 (0.44) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL6614504 | 1.00 | DNM1 (0.44) | DNM1CA12CA1CA2CA3 | |
| Hydrochloric Acid SCHEMBL6023728 | 0.97 | DNM1 (0.42) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL341868 | 0.97 | — | — | |
| SCHEMBL341549 | 0.88 | — | — | |
| Phosphonic Acid SCHEMBL8612224 | 0.82 | DNM1 (0.57) | DNM1CA12CA1CA2CA3 | |
| Phosphonic Acid SCHEMBL3029099 | 0.82 | DNM1 (0.57) | DNM1CA12CA1CA2CA3 | |
| SCHEMBL2519667 | 0.82 | — | — | |
| Butane SCHEMBL27839119 | 0.79 | DNM1 (0.38) | DNM1LMNATSHRBLMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341479-B1 | LNA-G PROCESS | ROCHE INNOVATION CT COPENHAGEN AS (DK) | 2019-12-18 | — | — | EP | disclosed |
| US-20190055550-A1 | LNA-G Process | ROCHE INNOVATION CENTER COPENHAGEN A/S (DK) | 2019-02-21 | — | — | US | disclosed |
| EP-1000071-B1 | GABA-C RECEPTOR ANTAGONISTS FOR STIMULATING MEMORY CAPACITY | POLYCHIP PHARMACEUTICALS PTY (AU) | 2004-11-17 | — | — | EP | disclosed |
| US-6632806-B1 | Administering compound having selective GABAc receptor antagonist activity | THE UNIVERSITY OF SYDNEY (AU) | 2003-10-14 | — | — | US | disclosed |
| EP-1000071-A4 | NEUROLOGICALLY-ACTIVE COMPOUNDS | POLYCHIP PHARMACEUTICALS PTY (AU) | 2001-02-28 | — | — | EP | disclosed |
| EP-1000071-A1 | NEUROLOGICALLY-ACTIVE COMPOUNDS | Polychip Pharmaceuticals Pty. Ltd. (AU) | 2000-05-17 | — | — | EP | disclosed |
| WO-1998058939-A1 | NEUROLOGICALLY-ACTIVE COMPOUNDS | POLYCHIP PHARMACEUTICALS PTY. LTD. (AU) | 1998-12-30 | — | — | WO | disclosed |