Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2805432 | 0.98 | NPSR1 (0.71) | NPSR1L3MBTL1LMNACYP2D6ALDH1A1 | |
| SCHEMBL124203 | 0.98 | NPSR1 (0.71) | NPSR1L3MBTL1LMNACYP2D6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8044881 | 0.97 | NPSR1 (0.69) | NPSR1L3MBTL1LMNACYP2D6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29676296 | 0.97 | NPSR1 (0.69) | NPSR1L3MBTL1LMNACYP2D6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6682577 | 0.97 | NPSR1 (0.69) | NPSR1L3MBTL1LMNACYP2D6ALDH1A1 | |
| SCHEMBL125500 | 0.97 | NPSR1 (0.73) | NPSR1L3MBTL1LMNACYP2D6ALDH1A1 | |
| SCHEMBL30057272 | 0.97 | NPSR1 (0.73) | NPSR1L3MBTL1LMNACYP2D6ALDH1A1 | |
| Bromide SCHEMBL5146792 | 0.95 | NPSR1 (0.71) | NPSR1L3MBTL1LMNACYP2D6ALDH1A1 | |
| Fluoride Ion SCHEMBL5148095 | 0.95 | NPSR1 (0.71) | NPSR1L3MBTL1LMNACYP2D6ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28530287 | 0.95 | NPSR1 (0.71) | NPSR1L3MBTL1LMNACYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10666004-B2 | Slipring with reduced contact noise | SCHLEIFRING GMBH (DE) | 2020-05-26 | — | — | US | claimed |
| US-20170346250-A1 | SLIPRING WITH REDUCED CONTACT NOISE | SCHLEIFRING GMBH (DE) | 2017-11-30 | — | — | US | claimed |
| US-6830674-B2 | Brightener additive and bath for alkaline cyanide-free zinc electroplating | COLUMBIA CHEMICAL CORPORATION | 2004-12-14 | — | — | US | claimed |
| US-10666004-B2 | Slipring with reduced contact noise | SCHLEIFRING GMBH (DE) | 2020-05-26 | — | — | US | disclosed |
| US-10666004-B2 | Slipring with reduced contact noise | SCHLEIFRING GMBH (DE) | 2020-05-26 | — | — | US | disclosed |
| US-20170346250-A1 | SLIPRING WITH REDUCED CONTACT NOISE | SCHLEIFRING GMBH (DE) | 2017-11-30 | — | — | US | disclosed |
| US-20170346250-A1 | SLIPRING WITH REDUCED CONTACT NOISE | SCHLEIFRING GMBH (DE) | 2017-11-30 | — | — | US | disclosed |
| US-6830674-B2 | Brightener additive and bath for alkaline cyanide-free zinc electroplating | COLUMBIA CHEMICAL CORPORATION | 2004-12-14 | — | — | US | disclosed |
| WO-2004044269-A2 | BRIGHTENER ADDITIVE AND BATH FOR ALKALINE CYANIDE-FREE ZINC ELECTROPLATING | COLUMBIA CHEMICAL CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |
| US-20040084322-A1 | Brightener additive and bath for alkaline cyanide-free zinc electroplating | COLUMBIA CHEMICAL CORPORATION | 2004-05-06 | — | — | US | disclosed |