Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 7/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154552 | 0.84 | GUSB (0.52) | S1PR1KDM4EALDH1A1MAPTRAB9A | |
| SCHEMBL9798590 | 0.76 | SMN1; SMN2 (0.47) | KDM4EALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL6682581 | 0.73 | PTGS1 (0.34) | KDM4EALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL28304139 | 0.66 | SMN1; SMN2 (0.47) | S1PR1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL18085139 | 0.65 | ALDH1A1 (0.42) | KDM4EALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL21614624 | 0.64 | KMO (0.40) | KDM4EALDH1A1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL12259927 | 0.64 | CYP3A4 (0.56) | KDM4EALDH1A1MAPTTDP1NPC1 | |
| SCHEMBL20341649 | 0.63 | ALDH1A1 (0.64) | S1PR1S1PR3KDM4EALDH1A1MAPT | |
| SCHEMBL22795275 | 0.63 | TDP1 (0.52) | KDM4EALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL12828098 | 0.63 | SMN1; SMN2 (0.51) | KDM4EALDH1A1MAPTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446110-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | Structural Bioinformatics Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003032916-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | STRUCTURAL BIOINFORMATICS INC. (US) | 2003-04-24 | — | — | WO | disclosed |