SCHEMBL6682705

SCHEMBL6682705

CCC(Cl)Cc1ccccc1Cl

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.45
PNMT P11086 1/20 0.45
ALDH1A1 P00352 1/20 0.45
SLC6A2 P23975 2/20 0.44
SLC6A4 P31645 2/20 0.44
SLC6A3 Q01959 2/20 0.44
TAAR1 Q96RJ0 3/20 0.42
LMNA P02545 1/20 0.42
AOC3 Q16853 1/20 0.40
PKM P14618 1/20 0.38
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
NPC1 O15118 1/20 0.38
PYCR1 P32322 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6681406 0.84 SLC6A2 (0.46) IDO1PNMTALDH1A1SLC6A2SLC6A4
SCHEMBL11217429 0.82 ALDH1A1 (0.42) IDO1PNMTALDH1A1SLC6A2SLC6A4
SCHEMBL21726735 0.81 IDO1 (0.46) IDO1PNMTALDH1A1SLC6A2SLC6A4
SCHEMBL11666236 0.81 IDO1 (0.46) IDO1PNMTSLC6A2SLC6A4SLC6A3
SCHEMBL6680628 0.80 SLC6A2 (0.59) IDO1PNMTALDH1A1SLC6A2SLC6A4
SCHEMBL8224139 0.79 SLC6A2 (0.48) IDO1PNMTALDH1A1SLC6A2SLC6A4
SCHEMBL6683031 0.78 SLC6A2 (0.52) IDO1PNMTALDH1A1SLC6A2SLC6A4
SCHEMBL23780015 0.78 SLC6A4 (0.52) IDO1PNMTALDH1A1SLC6A2SLC6A4
SCHEMBL6680434 0.78 TSHR (0.42) IDO1SLC6A2SLC6A4TAAR1LMNA
SCHEMBL16534463 0.78 ALDH1A1 (0.47) IDO1PNMTALDH1A1SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed