Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2878725 | 0.86 | TSHR (0.33) | IDO1PNMTTAAR1TSHR | |
| SCHEMBL6682705 | 0.81 | IDO1 (0.45) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL5654864 | 0.80 | PNMT (0.60) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL6681406 | 0.78 | SLC6A2 (0.46) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL29786842 | 0.77 | IDO1 (0.45) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL8791088 | 0.77 | HSPA5 (0.48) | IDO1TAAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8791057 | 0.77 | TP53 (0.32) | TSHR | |
| SCHEMBL8791083 | 0.77 | ALDH1A1 (0.31) | TSHR | |
| SCHEMBL14002931 | 0.76 | IDO1 (0.48) | IDO1PNMTTAAR1SLC6A2SLC6A4 | |
| SCHEMBL3335731 | 0.76 | IDO1 (0.48) | IDO1PNMTTAAR1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4092369-A | CHLORINATION OF CHLOROAROMATIC COMPOUND, ORGANIC SULFIDE CATALYST | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1978-05-30 | — | — | US | disclosed |