SCHEMBL6682822

SCHEMBL6682822

Cc1noc(=O)c2ccc(NC=O)cc12

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 19/20 0.45
PGR P06401 7/20 0.45
NR3C2 P08235 4/20 0.40
AR P10275 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6554510 0.78 NR3C1 (0.52) NR3C1PGRNR3C2AR
SCHEMBL13808484 0.75 ELANE (0.43) NR3C1PGR
SCHEMBL1262305 0.72 NPC1 (0.41) NR3C1PGR
SCHEMBL4163146 0.71 NR3C1 (0.53) NR3C1PGRNR3C2AR
SCHEMBL4176230 0.70 NR3C1 (0.46) NR3C1PGRNR3C2AR
SCHEMBL4278672 0.70 NR3C1 (0.52) NR3C1PGRNR3C2AR
SCHEMBL4173498 0.69 NR3C1 (0.49) NR3C1PGRNR3C2AR
SCHEMBL4173216 0.69 NR3C1 (0.67) NR3C1PGRNR3C2AR
SCHEMBL4167078 0.69 NR3C1 (0.47) NR3C1PGRNR3C2AR
SCHEMBL14112292 0.69 NR3C1 (0.62) NR3C1PGRNR3C2AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004071389-A2 NON-STEROIDAL INFALMMATION INHIBITORS GLAXO GROUP LIMITED (GB) 2004-08-26 WO disclosed