Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.55 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.52 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.52 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.52 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6682947 | 0.79 | GRIK1 (0.53) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL6341738 | 0.79 | GRIK1 (0.53) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL17165762 | 0.76 | GRIK1 (0.52) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL8877421 | 0.74 | GRIK1 (0.53) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL17165763 | 0.71 | GRIK1 (0.52) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| Butane SCHEMBL4661674 | 0.71 | GRIK1 (0.46) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL8399846 | 0.71 | GRIK1 (1.00) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL11226300 | 0.70 | GPR84 (0.45) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL13917775 | 0.70 | GRIK1 (0.46) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL6693083 | 0.69 | GRIK1 (0.33) | GRIK1GRIA1GRIA2GRIA4GRIK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219199-B1 | METHOD FOR PREPARATION OF LACTONES | COULSTON INTERNATIONAL CORPORATION (US) | 1991-07-31 | — | — | EP | disclosed |
| US-4772728-A | AND ALDEHYDE | ANGUS CHEMICAL COMPANY (US) | 1988-09-20 | — | — | US | disclosed |
| EP-0219199-A1 | Method for preparation of lactones | COULSTON INTERNATIONAL CORPORATION (US) | 1987-04-22 | — | — | EP | disclosed |