SCHEMBL6682968

SCHEMBL6682968

CCCCCC(F)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.44
HTR2A P28223 3/20 0.42
CSNK1E P49674 1/20 0.41
OPRM1 P35372 2/20 0.41
OPRD1 P41143 2/20 0.41
OPRK1 P41145 2/20 0.41
OPRL1 P41146 2/20 0.41
NAAA Q02083 2/20 0.40
POLB P06746 2/20 0.40
CNR2 P34972 1/20 0.40
MAPT P10636 2/20 0.39
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39
HRH1 P35367 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6685419 0.98 HTR2A (0.45) SIGMAR1HTR2ACSNK1EOPRM1OPRD1
SCHEMBL6680881 0.98 HTR2A (0.45) SIGMAR1HTR2ACSNK1EOPRM1OPRD1
SCHEMBL10400302 0.96 HTR2A (0.44) SIGMAR1HTR2ACSNK1EOPRM1OPRD1
Methyl Alcohol SCHEMBL27692954 0.94 CSNK1E (0.45) SIGMAR1HTR2ACSNK1EOPRM1OPRD1
SCHEMBL6681384 0.94 POLB (0.45) SIGMAR1HTR2AOPRM1OPRD1OPRK1
SCHEMBL14767588 0.85 AOC3 (0.46) SIGMAR1HTR2ALMNAHRH1
SCHEMBL844607 0.85 AOC3 (0.46) SIGMAR1HTR2ALMNAHRH1
SCHEMBL81907 0.80 SIGMAR1 (0.64) SIGMAR1HTR2AOPRM1LMNAHRH1
SCHEMBL28918758 0.79 HRH1 (0.42) SIGMAR1HTR2AHRH1
SCHEMBL8100113 0.78 SIGMAR1 (0.62) SIGMAR1HTR2ACSNK1ENAAAHRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed