SCHEMBL844607

SCHEMBL844607

CCCC(F)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 2/20 0.46
LMNA P02545 1/20 0.43
HRH1 P35367 7/20 0.40
HTR2A P28223 7/20 0.40
SIGMAR1 Q99720 1/20 0.39
TAAR1 Q96RJ0 3/20 0.38
RIPK1 Q13546 1/20 0.38
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14767588 1.00 AOC3 (0.46) AOC3LMNAHRH1HTR2ASIGMAR1
Acetic Acid SCHEMBL27813855 0.90 MTNR1A (0.44) AOC3LMNA
SCHEMBL27999449 0.87 CYP17A1 (0.46) TAAR1
SCHEMBL6681384 0.86 POLB (0.45) AOC3LMNAHRH1HTR2ASIGMAR1
SCHEMBL6682968 0.85 SIGMAR1 (0.44) LMNAHRH1HTR2ASIGMAR1
SCHEMBL6680881 0.83 HTR2A (0.45) HTR2ASIGMAR1
SCHEMBL6685419 0.83 HTR2A (0.45) HTR2ASIGMAR1
SCHEMBL10400302 0.81 HTR2A (0.44) HTR2ASIGMAR1
SCHEMBL3898638 0.80 LMNA (0.52) AOC3LMNAHRH1HTR2ATAAR1
SCHEMBL17816146 0.80 LMNA (0.52) AOC3LMNAHRH1HTR2ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108929210-A A kind of synthetic method of the fluoro- 2,2- dichloro propionic aldehyde of pesticide intermediate 3,3,3- tri- 江苏扬农化工集团有限公司 2018-12-04 CN claimed
EP-2707335-A1 OYXGEN-CAPTURING AGENTS FOR AQUEOUS SYSTEMS Arkema France (FR) 2014-03-19 EP claimed
WO-2012153058-A1 OYXGEN-CAPTURING AGENTS FOR AQUEOUS SYSTEMS ARKEMA FRANCE (FR) 2012-11-15 WO claimed
US-20260042715-A1 FLUORINATION PROCESS ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) 2026-02-12 US disclosed
EP-4565550-A1 FLUORINATION PROCESS Royal College of Surgeons in Ireland (IE) 2025-06-11 EP disclosed
EP-4381026-A1 COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE COMPOUND Idemitsu Kosan Co.,Ltd. (JP) 2024-06-12 EP disclosed
EP-4326731-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES Samsung Display Co., Ltd. (KR) 2024-02-28 EP disclosed
WO-2024028729-A1 FLUORINATION PROCESS ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) 2024-02-08 WO disclosed
WO-2023117835-A1 ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-06-29 WO disclosed
EP-4185655-A1 ORGANIC MOLECULES FOR OPTOELECTRONIC DEVICES Samsung Display Co., Ltd. (KR) 2023-05-31 EP disclosed
WO-2023057327-A1 METHOD FOR FORMING AN ORGANIC ELEMENT OF AN ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2023-04-13 WO disclosed
WO-2006085930-A9 METHOD OF PREPARING ALUMINUM NANORODS NANOMAT INC (US) 2006-10-05 WO disclosed
WO-2005087751-A2 SUBSTITUTED HYDROXYETHYLAMINE ASPARTYL PROTEASE INHIBITORS ELAN PHARMACEUTICALS, INC. (US) 2005-09-22 WO disclosed
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 EP disclosed
EP-1254101-A1 PROPIONIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF DIABETES AND OBESITY Novo Nordisk A/S (DK) 2002-11-06 EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
WO-2001055085-A1 PROPIONIC ACID DERIVATIVES AND THEIR USE IN THE TREATMENT OF DIABETES AND OBESITY NOVO NORDISK A/S (DK) 2001-08-02 WO disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed
EP-0773939-A1 DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS THE PROCTER & GAMBLE COMPANY (US) 1997-05-21 EP disclosed
WO-1996003396-A1 DIHYDROBENZOFURAN AND RELATED COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS THE PROCTER & GAMBLE COMPANY (US) 1996-02-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042715-A1 FLUORINATION PROCESS XDH, VGF, GTF2F1 AOC3 513/4885LMNA 1389/4885HRH1 2427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.