Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | KLK1 | P06870 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678956 | 0.84 | ALDH1A1 (0.38) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL6679213 | 0.77 | CYP2D6 (0.48) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL6682506 | 0.77 | SMN1; SMN2 (0.38) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL29115890 | 0.69 | CYP1A2 (0.49) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL29115798 | 0.69 | CYP1A2 (0.49) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL29115797 | 0.69 | CYP1A2 (0.49) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL6683073 | 0.68 | SLC6A3 (0.39) | PKMSLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7605459 | 0.66 | CYP1A2 (0.42) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL1937037 | 0.64 | CYP1A2 (0.44) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 | |
| SCHEMBL1321714 | 0.61 | NPSR1 (0.47) | CYP1A2SMN1; SMN2CYP2D6PKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |