Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28675818 | 0.89 | PARP10 (0.49) | PKMCYP19A1PARP10 | |
| SCHEMBL1793890 | 0.87 | PKM (0.63) | GAAPKMALDH1A1ELANENPSR1 | |
| SCHEMBL6333881 | 0.84 | GAA (0.59) | GAAPKMALDH1A1ELANENPSR1 | |
| SCHEMBL6285323 | 0.84 | GAA (0.59) | GAAPKMALDH1A1ELANENPSR1 | |
| SCHEMBL6683308 | 0.83 | CA1 (0.47) | GAAPKMELANECA12CA1 | |
| SCHEMBL1790037 | 0.82 | GAA (0.58) | GAAPKMALDH1A1ELANENPSR1 | |
| SCHEMBL51856 | 0.82 | GAA (0.58) | GAAPKMALDH1A1ELANENPSR1 | |
| SCHEMBL50786 | 0.82 | PKM (0.58) | GAAPKMALDH1A1ELANENPSR1 | |
| SCHEMBL6288097 | 0.82 | GAA (0.61) | GAAPKMALDH1A1ELANENPSR1 | |
| SCHEMBL6286860 | 0.82 | GAA (0.61) | GAAPKMALDH1A1ELANENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |