Thiobenzoic Acid

Thiobenzoic Acid

SCHEMBL6683183

C#N.CCCO.OC(=S)c1ccccc1.OC(=S)c1ccccc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.42
ATM Q13315 1/20 0.42
ALDH1A1 P00352 1/20 0.39
MAPT P10636 1/20 0.39
CES2 O00748 5/20 0.38
CES1 P23141 5/20 0.38
HSP90AA1 P07900 1/20 0.38
LMNA P02545 1/20 0.37
PTGS2 P35354 1/20 0.37
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC10 Q969S8 1/20 0.36
HDAC11 Q96DB2 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
HDAC9 Q9UKV0 1/20 0.36
HDAC5 Q9UQL6 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiobenzoic Acid SCHEMBL6677660 0.89 SMN1; SMN2 (0.43) POLBATMALDH1A1CES2CES1
Thiobenzoic Acid SCHEMBL28362258 0.82 ALDH1A1 (0.48) POLBATMALDH1A1MAPTCES2
Thiobenzoic Acid SCHEMBL6683304 0.82 CES2 (0.37) POLBALDH1A1MAPTCES2CES1
Thiobenzoic Acid SCHEMBL21633501 0.79 CES2 (0.47) ATMALDH1A1MAPTCES2CES1
Thiobenzoic Acid SCHEMBL28030107 0.78 CES2 (0.53) CES2CES1PTGS2
Thiobenzoic Acid SCHEMBL28659756 0.78 ALDH1A1 (0.44) POLBATMALDH1A1MAPTCES2
Thiobenzoic Acid SCHEMBL21980745 0.77 CES2 (0.46) ATMALDH1A1MAPTCES2CES1
Thiobenzoic Acid SCHEMBL2457293 0.77 KMT2A (0.37) POLBATMALDH1A1MAPTCES2
Thiobenzoic Acid SCHEMBL16210786 0.77 ALDH1A1 (0.40) POLBATMALDH1A1MAPTCES2
Thiobenzoic Acid SCHEMBL15282156 0.76 ALDH1A1 (0.50) POLBALDH1A1MAPTCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004046204-A1 PROCESS FOR THE RADICAL (CO)POLYMERIZATION OF A COMPOUND COMPRISING AT LEAST ONE NON-AROMATIC C=C DOUBLE BOND STICHTING DUTCH POLYMER INSTITUTE (NL) 2004-06-03 WO disclosed