Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.53 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | ATP4A | P20648 | 2/20 | 0.48 |
| ▸ | ATP4B | P51164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5126387 | 0.80 | KDM4E (0.55) | KMT2AMEN1ALDH1A1PKMMAPT | |
| SCHEMBL3412784 | 0.80 | MAPT (0.58) | GAAKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL5128486 | 0.80 | KDM4E (0.55) | LMNAHTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL2470980 | 0.80 | GAA (0.66) | GAALMNAHTTKMT2AMEN1 | |
| SCHEMBL2470984 | 0.80 | GAA (0.66) | GAALMNAHTTKMT2AMEN1 | |
| SCHEMBL5132595 | 0.79 | KMT2A (0.66) | LMNAKMT2AMEN1ALDH1A1PKM | |
| SCHEMBL3416255 | 0.76 | POLB (0.62) | GAALMNAHTTKMT2AMEN1 | |
| SCHEMBL4521944 | 0.75 | ROCK2 (0.56) | GAALMNAHTTKMT2AMEN1 | |
| SCHEMBL29013030 | 0.74 | LMNA (1.00) | GAALMNAHTTKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL4508678 | 0.74 | ROCK2 (0.55) | GAALMNAHTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3039126-A2 | SMALL MOLECULE CELLULAR REPROGRAMMING TO GENERATE NEURONAL CELLS | The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone (US) | 2016-07-06 | — | — | EP | disclosed |
| WO-2015041809-A2 | SMALL MOLECULE CELLULAR REPROGRAMMING TO GENERATE NEURONAL CELLS | THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLADSTONE (US) | 2015-03-26 | — | — | WO | disclosed |
| WO-2004062666-A2 | USE OF RHO-KINASE INHIBITORRS FOR TREATMENT OF BENIGN PROSTATIC HYPERPLASIA | UNIVERSITY COLLEGE LONDON (GB) | 2004-07-29 | — | — | WO | disclosed |