Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1776980 | 1.00 | PTGS2 (0.41) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL1777232 | 0.91 | NOS2 (0.42) | PTGS2CYP3A4HTTKDM4EALDH1A1 | |
| SCHEMBL2350903 | 0.90 | PTGS2 (0.37) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL9478817 | 0.89 | NOS2 (0.39) | PTGS2HTTKDM4EALDH1A1MAPT | |
| SCHEMBL19358148 | 0.83 | PTGS2 (0.55) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL19358155 | 0.83 | PTGS2 (0.55) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL19358152 | 0.83 | PTGS2 (0.55) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL1777432 | 0.83 | PTGS2 (0.55) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL19358108 | 0.83 | PTGS2 (0.55) | PTGS2CYP3A4ESR1ADRA2AADORA3 | |
| SCHEMBL19358002 | 0.83 | PTGS2 (0.55) | PTGS2CYP3A4ESR1ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456297-A1 | FLAMEPROOF MOLDING MATERIALS | Bayer Aktiengesellschaft (DE) | 2004-09-15 | — | — | EP | disclosed |
| WO-2004041933-A1 | FLAMEPROOF MOLDING MATERIALS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-05-21 | — | — | WO | disclosed |
| EP-0310979-A2 | Glass fibre reinforced flame retardant thermoplastic moulding compositions based on polyesters and graft polymers | BASF Aktiengesellschaft (DE) | 1989-04-12 | — | — | EP | disclosed |
| EP-0030618-B1 | FLAME-RESISTANT MOULDING MASSES BASED ON POLYETHYLENETEREPHTHALATE, PROCESS FOR THEIR PREPARATION AND THEIR USE IN PRODUCING MOULDINGS | BAYER AG (DE) | 1983-10-12 | — | — | EP | disclosed |