SCHEMBL668356

SCHEMBL668356

C=C(C)C(=O)OC.C=CC(=O)OCCCC.C=CC(=O)OCCCCCCCC

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.65
HPGD P15428 1/20 0.65
ALDH1A1 P00352 5/20 0.56
CYP3A4 P08684 1/20 0.56
HCAR2 Q8TDS4 3/20 0.46
ATM Q13315 1/20 0.46
EPHX1 P07099 1/20 0.42
NAAA Q02083 1/20 0.41
MAPT P10636 1/20 0.40
RAB9A P51151 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
TP53 P04637 2/20 0.40
HIF1A Q16665 2/20 0.40
HSD17B10 Q99714 1/20 0.40
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
FAAH O00519 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8349812 0.98 TSHR (0.63) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL7974959 0.98 TSHR (0.63) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL8958812 0.98 TSHR (0.63) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL11511400 0.98 TSHR (0.63) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL19350367 0.97 TSHR (0.67) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL27778295 0.97 TSHR (0.67) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL7532090 0.95 TSHR (0.71) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL521825 0.95 TSHR (0.71) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL5844442 0.95 TSHR (0.71) TSHRHPGDALDH1A1CYP3A4HCAR2
SCHEMBL35081 0.95 TSHR (0.71) TSHRHPGDALDH1A1CYP3A4HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070044810-A1 Method of enhanced drug application JR CHEM, LLC 2007-03-01 US claimed
US-20070003504-A1 Method of enhanced benzoyl peroxide application JR CHEM, LLC 2007-01-04 US claimed
WO-2007002880-A2 METHOD OF ENHANCED DRUG APPLICATION JR CHEM, LLC (US) 2007-01-04 WO claimed
US-20050013790-A1 External skin care composition KAO CORPORATION (JP) 2005-01-20 US claimed
WO-2024142783-A1 SUNSCREEN COSMETIC, METHOD FOR IMPROVING ULTRAVIOLET RAY PROTECTION FACTOR OF ULTRAVIOLET RAY ABSORBING AGENT, AND ULTRAVIOLET RAY PROTECTION FACTOR IMPROVING AGENT 株式会社資生堂 2024-07-04 WO disclosed
US-11801207-B2 Water-in-oil emulsion sunscreen cosmetic SHISEIDO COMPANY, LTD. (JP) 2023-10-31 US disclosed
EP-3213742-B1 WATER-IN-OIL EMULSION SUNSCREEN COSMETIC SHISEIDO CO LTD (JP) 2023-09-06 EP disclosed
CN-116270259-A Water-in-oil type emulsified sunscreen cosmetic 株式会社资生堂 2023-06-23 CN disclosed
CN-116270260-A Water-in-oil type emulsified sunscreen cosmetic 株式会社资生堂 2023-06-23 CN disclosed
CN-114344175-A Oil-in-water type emulsion cosmetic 株式会社资生堂 2022-04-15 CN disclosed
EP-3360534-B1 SPRAYABLE SUNSCREEN COSMETIC SHISEIDO CO LTD (JP) 2021-11-24 EP disclosed
CN-108366916-B Spray type sunscreen cosmetic 株式会社资生堂 2020-04-28 CN disclosed
WO-2007005469-A2 METHOD OF ENHANCED BENZOYL PEROXIDE APPLICATION JR CHEM, LLC (US) 2007-01-11 WO disclosed
US-20070003504-A1 Method of enhanced benzoyl peroxide application JR CHEM, LLC 2007-01-04 US disclosed
EP-0846461-B1 OIL-IN-WATER EMULSION COMPOSITION AND OIL-IN-WATER EMULSIFIER SHISEIDO CO LTD (JP) 2005-11-02 EP disclosed
US-6878378-B1 External skin care composition KAO CORPORATION (JP) 2005-04-12 US disclosed
US-20050013790-A1 External skin care composition KAO CORPORATION (JP) 2005-01-20 US disclosed
EP-1051965-A2 External skin care composition Kao Corporation (JP) 2000-11-15 EP disclosed
US-6074652-A MIXTURE OF AN MONOALKYL GLYCERYL ETHER, WAX AND SILICONE OIL SHISEIDO CO., LTD. (JP) 2000-06-13 US disclosed
EP-0846461-A1 OIL-IN-WATER EMULSION COMPOSITION AND OIL-IN-WATER EMULSIFIER SHISEIDO COMPANY LIMITED (JP) 1998-06-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11801207-B2 Water-in-oil emulsion sunscreen cosmetic TYR, CUTA, LBR TSHR 806/4885HPGD 2231/4885ALDH1A1 2965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.