Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 11/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 11/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28456750 | 0.92 | AGTR1 (0.54) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL7270083 | 0.89 | AGTR1 (0.54) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL7272040 | 0.88 | AGTR1 (0.52) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL2816 | 0.88 | AGTR1 (0.52) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL10033 | 0.87 | AGTR1 (0.70) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL2673 | 0.86 | AGTR1 (0.58) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL2935 | 0.86 | AGTR1 (0.56) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL1844 | 0.84 | AGTR1 (0.49) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL2118 | 0.84 | AGTR1 (0.55) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL7271855 | 0.83 | AGTR1 (0.51) | AGTR1LTB4R2ABCB11GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474402-A1 | SALTS OF VALSARTAN | Novartis AG (CH) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003066606-A1 | SALTS OF VALSARTAN | NOVARTIS AG (CH) | 2003-08-14 | — | — | WO | disclosed |