Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 12/20 | 0.52 |
| ▸ | LTB4R2 | Q9NPC1 | 10/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.49 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28456750 | 0.93 | AGTR1 (0.54) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL2816 | 0.90 | AGTR1 (0.52) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL7270083 | 0.90 | AGTR1 (0.54) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL1844 | 0.89 | AGTR1 (0.49) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| SCHEMBL6683646 | 0.88 | AGTR1 (0.54) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL2118 | 0.87 | AGTR1 (0.55) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| SCHEMBL2789 | 0.86 | AGTR1 (0.55) | AGTR1LTB4R2ABCB11GP6AGTR2 | |
| SCHEMBL10033 | 0.86 | AGTR1 (0.70) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL3138 | 0.86 | AGTR1 (0.55) | AGTR1LTB4R2ABCB11GP6 | |
| SCHEMBL2969136 | 0.85 | AGTR1 (0.58) | AGTR1LTB4R2ABCB11GP6AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443983-A1 | Acyl compounds | CIBA-GEIGY AG (CH) | 1991-08-28 | — | — | EP | disclosed |