SCHEMBL6683676

SCHEMBL6683676

CC(Cl)CCCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 7/20 0.47
L3MBTL1 Q9Y468 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
MAOA P21397 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2239690 0.86 MEN1 (0.49) MEN1KMT2A
SCHEMBL2408105 0.82 SIGMAR1 (0.48) SIGMAR1MAOA
SCHEMBL19090603 0.82 SIGMAR1 (0.50) SIGMAR1L3MBTL1MEN1KMT2AMAOA
SCHEMBL108633 0.82 LMNA (0.54) SIGMAR1L3MBTL1
Hydrochloric Acid SCHEMBL30514257 0.80 LMNA (0.53) SIGMAR1MEN1KMT2A
SCHEMBL10597968 0.79 SIGMAR1 (0.44) SIGMAR1L3MBTL1MEN1KMT2A
SCHEMBL8325572 0.78 SIGMAR1 (0.47) SIGMAR1L3MBTL1MEN1KMT2AMAOA
SCHEMBL3712834 0.78 SLC6A2 (0.56) SIGMAR1MAOA
SCHEMBL10473337 0.78 GRIK1 (0.54) MEN1KMT2A
SCHEMBL5609991 0.78 HDAC3 (0.47) SIGMAR1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 EP disclosed
EP-0832886-B1 Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them SERVIER LAB (FR) 2002-11-13 EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed
US-5889003-A PHOSPHODIESTERASE INHIBITOR ADIR ET COMPAGNIE (FR) 1999-03-30 US disclosed
EP-0832886-A1 Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1998-04-01 EP disclosed