Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 8/20 | 0.53 |
| ▸ | BUB1 | O43683 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6688213 | 0.87 | FABP4 (0.69) | FABP4BUB1FABP3 | |
| SCHEMBL6695587 | 0.86 | FABP4 (0.50) | FABP4KDM4EMEN1KMT2AUSP2 | |
| SCHEMBL6695590 | 0.86 | FABP4 (0.50) | FABP4KDM4EMEN1KMT2AUSP2 | |
| SCHEMBL6682158 | 0.85 | FABP4 (0.72) | FABP4FABP3 | |
| SCHEMBL6687192 | 0.85 | FABP4 (0.57) | FABP4HDAC1HDAC6FABP3CSNK2A2 | |
| SCHEMBL6690088 | 0.83 | FABP4 (0.76) | FABP4KDM4EALDH1A1FABP3 | |
| SCHEMBL6683246 | 0.83 | FABP4 (0.57) | FABP4HDAC1HDAC6FABP3CSNK2A2 | |
| SCHEMBL6681846 | 0.82 | FABP4 (0.77) | FABP4FABP3 | |
| SCHEMBL6692803 | 0.76 | FABP4 (0.66) | FABP4KDM4EHDAC1HDAC6FABP3 | |
| SCHEMBL6683944 | 0.76 | FABP4 (0.47) | FABP4HDAC1HDAC6BRD4FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063156-A1 | NOVEL INDOLE DERIVATES AS FABP-4 INHIBITORS | BIOVITRUM AB (SE) | 2004-07-29 | — | — | WO | claimed |
| WO-2004063156-A1 | NOVEL INDOLE DERIVATES AS FABP-4 INHIBITORS | BIOVITRUM AB (SE) | 2004-07-29 | — | — | WO | disclosed |