Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 15/20 | 0.57 |
| ▸ | FABP3 | P05413 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683246 | 0.98 | FABP4 (0.57) | FABP4FABP3HDAC1HDAC6CSNK2A2 | |
| SCHEMBL6691727 | 0.88 | FABP4 (0.74) | FABP4FABP3HDAC1HDAC6CSNK2A2 | |
| SCHEMBL6687514 | 0.87 | FABP4 (0.54) | FABP4FABP3MAPK8 | |
| SCHEMBL6687511 | 0.87 | FABP4 (0.54) | FABP4FABP3MAPK8 | |
| SCHEMBL6685674 | 0.85 | FABP4 (0.74) | FABP4FABP3 | |
| SCHEMBL6683705 | 0.85 | FABP4 (0.53) | FABP4FABP3HDAC1HDAC6CSNK2A2 | |
| SCHEMBL6683944 | 0.85 | FABP4 (0.47) | FABP4FABP3HDAC1HDAC6 | |
| SCHEMBL6686562 | 0.84 | FABP4 (0.76) | FABP4FABP3 | |
| SCHEMBL6685978 | 0.84 | FABP4 (0.77) | FABP4FABP3 | |
| SCHEMBL5207833 | 0.83 | HDAC1 (0.51) | FABP4FABP3HDAC1HDAC6CSNK2A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063156-A1 | NOVEL INDOLE DERIVATES AS FABP-4 INHIBITORS | BIOVITRUM AB (SE) | 2004-07-29 | — | — | WO | claimed |
| WO-2004063156-A1 | NOVEL INDOLE DERIVATES AS FABP-4 INHIBITORS | BIOVITRUM AB (SE) | 2004-07-29 | — | — | WO | disclosed |