Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683859 | 1.00 | TAS1R3 (0.47) | TAS1R3TAS1R1ALDH1A1RAB9ANPC1 | |
| SCHEMBL5551407 | 0.78 | TAS1R3 (0.50) | TAS1R3TAS1R1ALDH1A1RAB9ANPC1 | |
| SCHEMBL5551410 | 0.78 | TAS1R3 (0.50) | TAS1R3TAS1R1ALDH1A1RAB9ANPC1 | |
| SCHEMBL28657395 | 0.77 | MAOB (0.48) | ALDH1A1RAB9ANPC1LMNATHRB | |
| SCHEMBL6815286 | 0.77 | RAB9A (0.68) | ALDH1A1RAB9ANPC1LMNAL3MBTL1 | |
| SCHEMBL29926214 | 0.76 | MAPT (0.60) | ALDH1A1RAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL8605861 | 0.75 | MAOB (0.48) | ALDH1A1RAB9ANPC1LMNAL3MBTL1 | |
| SCHEMBL6655449 | 0.74 | FLT3 (0.57) | TAS1R3TAS1R1ALDH1A1RAB9ANPC1 | |
| SCHEMBL6655445 | 0.74 | FLT3 (0.57) | TAS1R3TAS1R1ALDH1A1RAB9ANPC1 | |
| SCHEMBL7104948 | 0.74 | MAPT (0.60) | ALDH1A1RAB9ANPC1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061134-A9 | ANTIMICROBIAL AGENTS | BRITISH BIOTECH PHARM (GB) | 2004-04-22 | — | — | WO | disclosed |
| US-6716878-B1 | BACTERICIDE, ANTIPROTOZOAL; VANCOMYCIN RESISTANT ENTEROCOCCI AND BETA-LACTAM ANTIBIOTIC-RESISTANT BACTERIA, METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; HYDROXAMIC ACID AND N-FORMYL SUBTITUTED ALKYLAMIDES | VERNALIS (OXFORD) LIMITED (GB) | 2004-04-06 | — | — | US | disclosed |