Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27414736 | 0.84 | MAPK1 (0.44) | MAPK1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL11095319 | 0.75 | MAPT (0.44) | MAPK1SMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL25735678 | 0.74 | MAPK1 (0.50) | MAPK1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11189485 | 0.72 | MAPK1 (0.51) | MAPK1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL25915799 | 0.71 | MAPK1 (0.43) | MAPK1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL15042238 | 0.70 | MAPK1 (0.40) | MAPK1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL11092210 | 0.69 | SMN1; SMN2 (0.45) | MAPK1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL4479461 | 0.69 | HPGD (0.44) | MAPK1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL14701605 | 0.69 | HPGD (0.47) | MAPK1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL23108977 | 0.68 | HPGD (0.50) | MAPK1SMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480978-A1 | PROCESS FOR PREPARING 3-(2-(4-(6-FLUOROBENZO(D) ISOXAZOL-3-YL)-PIPERIDIN-1YL)-ETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO-(1,2-A) PYRIMIDIN-4-ONE | FERRER INTERNACIONAL, S.A. (ES) | 2004-12-01 | — | — | EP | disclosed |
| WO-2003074522-A1 | PROCESS FOR PREPARING 3-(2-(4-(6-FLUOROBENZO(D) ISOXAZOL-3-YL)-PIPERIDIN-1YL)-ETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO-(1,2-A) PYRIMIDIN-4-ONE | FERRER INTERNACIONAL, S.A. (ES) | 2003-09-12 | — | — | WO | disclosed |