Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683908 | 0.84 | MAPK1 (0.40) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11095319 | 0.80 | MAPT (0.44) | MAPK1SMN1; SMN2ALDH1A1MAPTHPGD | |
| SCHEMBL25735678 | 0.79 | MAPK1 (0.50) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14701605 | 0.77 | HPGD (0.47) | MAPK1NPSR1TSHRSMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL11189485 | 0.77 | MAPK1 (0.51) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL23108977 | 0.76 | HPGD (0.50) | MAPK1NPSR1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL25915799 | 0.75 | MAPK1 (0.43) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL15042238 | 0.74 | MAPK1 (0.40) | MAPK1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11092210 | 0.74 | SMN1; SMN2 (0.45) | MAPK1NPSR1TSHRSMN1; SMN2MEN1 | |
| SCHEMBL25909784 | 0.73 | MAP4K1 (0.33) | LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137502-A2 | PNU ANTHRACYCLINE-DERIVED LINKER-PAYLOADS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2024-06-27 | — | — | WO | disclosed |