Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25735678 | 0.78 | MAPK1 (0.50) | MAPK1SMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL10183044 | 0.76 | MAPK1 (0.47) | MAPK1SMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL27414736 | 0.75 | MAPK1 (0.44) | MAPK1SMN1; SMN2ALDH1A1HPGDMEN1 | |
| Hydrochloric Acid SCHEMBL11189485 | 0.75 | MAPK1 (0.51) | MAPK1SMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL10183602 | 0.75 | MAPK1 (0.50) | MAPK1SMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL15042238 | 0.73 | MAPK1 (0.40) | MAPK1SMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL11092210 | 0.73 | SMN1; SMN2 (0.45) | MAPK1SMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL11183146 | 0.71 | ALDH1A1 (0.43) | MAPK1SMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL6683908 | 0.71 | MAPK1 (0.40) | MAPK1SMN1; SMN2ALDH1A1HPGDMEN1 | |
| SCHEMBL10183038 | 0.70 | AR (0.44) | MAPK1SMN1; SMN2ALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |