Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | DRD1 | P21728 | 3/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13657611 | 0.90 | KMT2A (0.44) | HTR2ACNR1FPR2SLC6A2SLC6A4 | |
| SCHEMBL30338449 | 0.86 | HTR2A (0.45) | HTR2ACNR1FPR2SLC6A2SLC6A4 | |
| SCHEMBL28878284 | 0.81 | HTR2A (0.41) | HTR2ACNR1FPR2SLC6A2SLC6A4 | |
| SCHEMBL10775330 | 0.81 | CYP1A2 (0.47) | HTR2ACNR1PYCR1KMT2ACYP1A2 | |
| SCHEMBL19901495 | 0.81 | ESR1 (0.47) | HTR2AFPR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7060140 | 0.80 | HTR2A (0.52) | HTR2ASLC6A2SLC6A4SLC6A3CHRM2 | |
| SCHEMBL14288440 | 0.80 | HTR2A (0.53) | HTR2ACNR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30620707 | 0.80 | BDKRB2 (0.41) | HTR2ACNR1CYP2D6LMNANFKB1 | |
| SCHEMBL6173982 | 0.79 | PYCR1 (0.39) | HTR2AFPR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16186720 | 0.79 | PYCR1 (0.43) | HTR2AFPR2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999064041-A9 | MULTIBINDING AGENTS THAT MODULATE NMDA RECEPTORS | ADVANCED MEDICINE INC (US) | 2001-05-31 | — | — | WO | disclosed |