Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.56 |
| ▸ | MEN1 | O00255 | 8/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838275 | 0.84 | KMT2A (0.69) | KMT2AMEN1LMNAHTTKDM4E | |
| SCHEMBL6832453 | 0.84 | KMT2A (0.57) | KMT2AMEN1LMNAHTTKDM4E | |
| SCHEMBL6838294 | 0.84 | MEN1 (0.67) | KMT2AMEN1LMNAHTTKDM4E | |
| SCHEMBL6838330 | 0.82 | LMNA (0.73) | KMT2AMEN1LMNAHTTKDM4E | |
| SCHEMBL6698237 | 0.74 | KMT2A (0.40) | KMT2AMEN1LMNAHTTKDM4E | |
| SCHEMBL24034414 | 0.73 | KMT2A (0.69) | KMT2AMEN1LMNAHTTKDM4E | |
| SCHEMBL6666685 | 0.73 | MAPT (0.56) | KMT2AMEN1LMNAHTTKDM4E | |
| SCHEMBL2369149 | 0.72 | MEN1 (0.71) | KMT2AMEN1LMNAHTTKDM4E | |
| SCHEMBL14969443 | 0.72 | KMT2A (0.53) | KMT2AMEN1NOD2 | |
| SCHEMBL6838309 | 0.69 | LMNA (0.56) | KMT2AMEN1LMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014850-A2 | SUBSTITUTED AMINOPYRIMIDINES AS NEUROKININ ANTAGONISTS | PREDIX PHARMACEUTICALS HOLDINGS, INC. (US) | 2004-02-19 | — | — | WO | disclosed |