Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.72 |
| ▸ | MALT1 | Q9UDY8 | 9/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681738 | 0.90 | PTGS2 (0.58) | PTGS2PTGS1MALT1 | |
| SCHEMBL6682132 | 0.89 | PTGS2 (0.53) | PTGS2PTGS1MALT1 | |
| SCHEMBL6685203 | 0.88 | PTGS2 (0.74) | PTGS2PTGS1MALT1 | |
| SCHEMBL6132289 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1MALT1 | |
| SCHEMBL6683996 | 0.84 | PTGS2 (0.81) | PTGS2PTGS1MALT1 | |
| SCHEMBL6686713 | 0.84 | PTGS2 (0.81) | PTGS2PTGS1MALT1 | |
| SCHEMBL6687179 | 0.84 | PTGS2 (0.71) | PTGS2PTGS1MALT1 | |
| SCHEMBL3354633 | 0.82 | PTGS2 (0.80) | PTGS2PTGS1 | |
| SCHEMBL5149036 | 0.80 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL6694687 | 0.79 | PTGS1 (0.68) | PTGS2PTGS1MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |