SCHEMBL6132289

SCHEMBL6132289

COc1ccc(-c2nc(OCC(F)(F)F)nn2-c2ccc(OC)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 11/20 1.00
PTGS1 P23219 9/20 1.00
MALT1 Q9UDY8 3/20 0.52
CYP1A2 P05177 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CYP3A4 P08684 1/20 0.44
TSHR P16473 1/20 0.44
THPO P40225 1/20 0.44
BLM P54132 1/20 0.44
PMP22 Q01453 1/20 0.44
HIF1A Q16665 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6683996 0.90 PTGS2 (0.81) PTGS2PTGS1MALT1CYP1A2CYP2C9
SCHEMBL6686713 0.90 PTGS2 (0.81) PTGS2PTGS1MALT1L3MBTL1
SCHEMBL6132303 0.90 PTGS2 (0.81) PTGS2PTGS1MALT1CYP1A2CYP2C9
SCHEMBL6132346 0.90 PTGS2 (0.81) PTGS2PTGS1MALT1CYP1A2CYP2C9
SCHEMBL3354633 0.89 PTGS2 (0.80) PTGS2PTGS1
SCHEMBL6685203 0.86 PTGS2 (0.74) PTGS2PTGS1MALT1L3MBTL1
SCHEMBL4031131 0.85 PTGS2 (0.81) PTGS2PTGS1MALT1L3MBTL1
SCHEMBL6684037 0.85 PTGS2 (0.72) PTGS2PTGS1MALT1
SCHEMBL6687179 0.84 PTGS2 (0.71) PTGS2PTGS1MALT1CYP2C9CYP2C19
SCHEMBL4026247 0.84 PTGS1 (0.76) PTGS2PTGS1MALT1L3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 336 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4142283-B1 METHOD OF GENERATING INFRARED IMAGE Aptiv Technologies AG (CH) 2025-10-22 EP claimed
US-PP36647-P2 Strawberry plant named ‘PS-13.467.089’ Plant Sciences, Inc. (US) 2025-05-06 US claimed
US-12282021-B2 Stratification of acute myeloid leukaemia patients for sensitivity to kinase pathway inhibitor therapy KINOMICA LIMITED (GB) 2025-04-22 US claimed
EP-4211989-B1 COMPACT CONTROL FOR LAMPS IN A MOTOR VEHICLE ELMOS SEMICONDUCTOR SE (DE) 2024-12-18 EP claimed
EP-3642627-B1 STRATIFICATION OF ACUTE MYELOID LEUKAEMIA PATIENTS FOR SENSITIVITY TO KINASE PATHWAY INHIBITOR THERAPY KINOMICA LTD (GB) 2024-09-04 EP claimed
CN-114593475-B Control method for water chilling unit 青岛海尔空调电子有限公司 2024-06-07 CN claimed
CN-115322190-B Pyridoimidazole acyl sulfonamide derivative, and preparation method and application thereof 山东大学 2023-09-22 CN claimed
EP-4142283-A1 METHOD OF GENERATING INFRARED IMAGE Aptiv Technologies Limited (BB) 2023-03-01 EP claimed
CN-110311660-B Self-adaptive single event upset resistant D trigger 西安微电子技术研究所 2023-02-24 CN claimed
CN-110190833-B Self-detection and self-recovery synchronous reset D trigger resisting single event upset 西安微电子技术研究所 2023-02-07 CN claimed
CN-110311656-B Self-adaptive single event upset resistant asynchronous reset and set D trigger 西安微电子技术研究所 2023-01-31 CN claimed
CN-114593475-A Control method for water chilling unit 青岛海尔空调电子有限公司 2022-06-07 CN claimed
CN-112050747-B Brillouin strength and frequency shift strain temperature coefficient automatic test system and method 中电科思仪科技股份有限公司 2022-02-25 CN claimed
CN-114048554-A Three-dimensional matching iteration method for aircraft engine 中国航发沈阳发动机研究所 2022-02-15 CN claimed
US-20030191155-A1 Triazole derivatives ASTELLAS PHARMA INC. (JP) 2003-10-09 US claimed
US-20260148046-A1 NEURAL PROCESSING UNIT OPERABLE IN MULTIPLE MODES TO APPROXIMATE ACTIVATION FUNCTION DEEPX CO., LTD. (KR) 2026-05-28 US disclosed
US-12625338-B2 Fan-in/Fan-out device KOHOKU KOGYO CO., LTD. (JP) 2026-05-12 US disclosed
EP-2581084-A1 SOLID DISPERSION COMPRISING TRIAZOLE COMPOUND Astellas Pharma Inc. (JP) 2013-04-17 EP disclosed
US-6927230-B2 Triazole derivatives FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2005-08-09 US disclosed
US-20030191155-A1 Triazole derivatives ASTELLAS PHARMA INC. (JP) 2003-10-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260148046-A1 NEURAL PROCESSING UNIT OPERABLE IN MULTIPLE MODES TO APPROXIMATE ACTIVATION FUNCTION PAFAH1B2, PAFAH1B3, NCDN PTGS2 3188/4885PTGS1 3769/4885MALT1 4221/4885
US-20030191155-A1 Triazole derivatives CBR1, CBR3, CYP1B1 PTGS2 2680/4885PTGS1 1504/4885MALT1 71/4885
US-12625338-B2 Fan-in/Fan-out device FSCN1, FMNL1, FOXO1 PTGS2 4851/4885PTGS1 4845/4885MALT1 1546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.