Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | HTR2C | P28335 | 9/20 | 0.53 |
| ▸ | HTR2B | P41595 | 6/20 | 0.53 |
| ▸ | HTR2A | P28223 | 5/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5680153 | 0.85 | HTR2C (0.70) | MAOAHTR2CHTR2BHTR2AMAOB | |
| SCHEMBL23191934 | 0.82 | HTR2C (0.66) | MAOAHTR2CHTR2BHTR2AMAOB | |
| Ammonia Solution, Strong SCHEMBL5834701 | 0.79 | HTR2C (0.55) | MAOAHTR2CHTR2BHTR2AMAOB | |
| 4-Phenyl-Butylamine SCHEMBL132472 | 0.76 | MAOA (1.00) | MAOAHTR2AMAOBSIGMAR1 | |
| SCHEMBL169336 | 0.74 | MAOA (0.95) | MAOAHTR2AMAOBSIGMAR1 | |
| SCHEMBL12598856 | 0.74 | MAOA (0.95) | MAOAHTR2AMAOBSIGMAR1 | |
| SCHEMBL4869500 | 0.74 | MAOA (0.95) | MAOAHTR2AMAOBSIGMAR1 | |
| SCHEMBL7337107 | 0.74 | MAOA (0.95) | MAOAHTR2AMAOBSIGMAR1 | |
| 4-Phenyl-Butylamine SCHEMBL8003688 | 0.74 | MAOA (0.95) | MAOAHTR2AMAOBSIGMAR1 | |
| SCHEMBL8501696 | 0.74 | MAOA (0.95) | MAOAHTR2AMAOBSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071445-A2 | 2-(AMINOMETHYL)ARYLAMIDE ANALGESICS | PHARMACOPEIA DRUG DISCOVERY, INC. (US) | 2004-08-26 | — | — | WO | disclosed |