Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.70 |
| ▸ | MAOB | P27338 | 10/20 | 0.70 |
| ▸ | HTR2B | P41595 | 6/20 | 0.70 |
| ▸ | HTR2A | P28223 | 4/20 | 0.70 |
| ▸ | MAOA | P21397 | 7/20 | 0.50 |
| ▸ | KDM1A | O60341 | 5/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23191934 | 0.88 | HTR2C (0.66) | HTR2CMAOBHTR2BHTR2AMAOA | |
| 4-Phenyl-Butylamine SCHEMBL6684091 | 0.85 | MAOA (0.58) | HTR2CMAOBHTR2BHTR2AMAOA | |
| SCHEMBL4144327 | 0.83 | HTR2C (1.00) | HTR2CMAOBHTR2BHTR2ASLC6A2 | |
| SCHEMBL2470140 | 0.83 | HTR2C (1.00) | HTR2CMAOBHTR2BHTR2ASLC6A2 | |
| SCHEMBL4129782 | 0.83 | HTR2C (1.00) | HTR2CMAOBHTR2BHTR2ASLC6A2 | |
| SCHEMBL13742111 | 0.83 | HTR2C (1.00) | HTR2CMAOBHTR2BHTR2ASLC6A2 | |
| Hydrochloric Acid SCHEMBL4135410 | 0.81 | HTR2C (1.00) | HTR2CMAOBHTR2BHTR2ASLC6A2 | |
| Hydrochloric Acid SCHEMBL4140547 | 0.81 | HTR2C (1.00) | HTR2CMAOBHTR2BHTR2ASLC6A2 | |
| Hydrochloric Acid SCHEMBL4135406 | 0.81 | HTR2C (1.00) | HTR2CMAOBHTR2BHTR2ASLC6A2 | |
| SCHEMBL25262357 | 0.79 | HTR2C (0.59) | HTR2CMAOBHTR2BHTR2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006094201-A2 | SEMICARBAZIDE-SENSITIVE AMIDE OXIDASE INHIBITORS | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2006-09-08 | — | — | WO | disclosed |
| US-7084154-B2 | 2-(aminomethyl) arylamide analgesics | PHARMACOPEIA DRUG DISCLOVERY, INC. (US) | 2006-08-01 | — | — | US | disclosed |
| EP-1663954-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT OF DISEASES | LA JOLLA PHARMACEUTICAL CO. (US) | 2006-06-07 | — | — | EP | disclosed |
| US-20050096360-A1 | Inhibitors of semicarbazide-sensitive amine oxidase (SSAO) and VAP-1 mediated adhesion useful for treatment of diseases | LA JOLLA PHARMACEUTICALS COMPANY | 2005-05-05 | — | — | US | disclosed |
| WO-2005014530-A2 | INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT OF DISEASES | LA JOLLA PHARMACEUTICAL CO. (US) | 2005-02-17 | — | — | WO | disclosed |
| US-20040167119-A1 | 2-(aminomethyl) arylamide analgesics | PHARMACOPEIA, INC (US) | 2004-08-26 | — | — | US | disclosed |
| WO-2004071445-A2 | 2-(AMINOMETHYL)ARYLAMIDE ANALGESICS | PHARMACOPEIA DRUG DISCOVERY, INC. (US) | 2004-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096360-A1 | Inhibitors of semicarbazide-sensitive amine oxidase (SSAO) and VAP-1 mediated adhesion useful for treatment of diseases | VCAM1, AOC2, AOC3 | HTR2C 2339/4885MAOB 71/4885HTR2B 1566/4885 |
| US-20040167119-A1 | 2-(aminomethyl) arylamide analgesics | OPRL1, OPRM1, OPRK1 | HTR2C 36/4885MAOB 420/4885HTR2B 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.