Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | F11 | P03951 | 7/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19598444 | 0.76 | NPC1 (0.43) | SIGMAR1NPY1RNPY5RNPC1RAB9A | |
| SCHEMBL11599527 | 0.67 | SIGMAR1 (0.42) | SIGMAR1PRSS1NPY1RNPY5RSLC6A4 | |
| SCHEMBL493565 | 0.66 | CNR1 (0.40) | F10PRSS1PRKCQSLC6A4NPC1 | |
| SCHEMBL8476760 | 0.64 | CYP2D6 (0.53) | SLC6A4SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL5455397 | 0.64 | FFAR2 (0.38) | F10PRSS1SLC6A4NPC1RAB9A | |
| SCHEMBL14606888 | 0.64 | GBA1 (0.59) | NPY5RMEN1KMT2A | |
| SCHEMBL14606884 | 0.64 | GBA1 (0.59) | NPY5RMEN1KMT2A | |
| SCHEMBL493821 | 0.64 | BCL2A1 (0.40) | F10PRSS1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL3637783 | 0.63 | KMT2A (0.64) | NPC1RAB9AL3MBTL1MEN1KMT2A | |
| SCHEMBL20625942 | 0.63 | HDAC6 (0.49) | NPY5RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073709-A1 | ANTIMICROBIAL AGENTS | PROLYSIS LIMITED (GB) | 2004-09-02 | — | — | WO | disclosed |