Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9821321 | 0.94 | TSHR (0.50) | TSHRADRA1DADRA1AADRA1BGSK3B | |
| SCHEMBL6495319 | 0.94 | TSHR (0.49) | TSHRADRA1DADRA1AADRA1BGSK3B | |
| SCHEMBL6528311 | 0.93 | TSHR (0.50) | TSHRADRA1DADRA1AADRA1BGSK3B | |
| SCHEMBL668453 | 0.88 | TSHR (0.56) | TSHRADRA1DADRA1AADRA1BGSK3B | |
| SCHEMBL3939476 | 0.82 | TSHR (0.46) | TSHRADRA1DADRA1AADRA1BGSK3B | |
| SCHEMBL9708708 | 0.81 | GSK3A (0.49) | TSHRGSK3BKMT2ALMNAALDH1A1 | |
| SCHEMBL11512914 | 0.80 | GAA (0.43) | TSHRADRA1DADRA1AADRA1BKMT2A | |
| SCHEMBL11284225 | 0.79 | ALDH1A1 (0.46) | TSHRKMT2ALMNAALDH1A1GAA | |
| SCHEMBL12717220 | 0.79 | ALDH1A1 (0.46) | TSHRKMT2ALMNAALDH1A1GAA | |
| SCHEMBL31632727 | 0.78 | GAA (0.49) | TSHRADRA1DADRA1AADRA1BPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021568-A | Lactam-1-acetic acid carbalkoxymethyl esters and method for preparing same | SHIPOV ALEXANDR G (SU) | 1991-06-04 | — | — | US | disclosed |