Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | PTGFR | P43088 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6645382 | 0.90 | KMT2A (0.38) | GLAKMT2AALDH1A1HIF1ATAAR1 | |
| SCHEMBL317640 | 0.79 | KMT2A (0.38) | GLAKMT2AHIF1ASMN1; SMN2CYP3A4 | |
| SCHEMBL17917764 | 0.78 | RAB9A (0.50) | KMT2AALDH1A1HIF1ASMN1; SMN2RAB9A | |
| SCHEMBL319697 | 0.76 | KMT2A (0.41) | GLAKMT2AHIF1ATAAR1SMN1; SMN2 | |
| SCHEMBL6502889 | 0.76 | PIK3CD (0.43) | KMT2ACNR2MEN1 | |
| SCHEMBL16541062 | 0.74 | LMNA (0.45) | GLAKMT2ASMN1; SMN2CYP3A4RAB9A | |
| SCHEMBL7081843 | 0.73 | TAAR1 (0.41) | KMT2AALDH1A1TAAR1SMN1; SMN2PTGFR | |
| SCHEMBL4614052 | 0.72 | KMT2A (0.39) | GLAKMT2AALDH1A1HIF1ATAAR1 | |
| SCHEMBL16540928 | 0.72 | GLA (0.40) | GLAKMT2AALDH1A1HIF1ASMN1; SMN2 | |
| SCHEMBL4583705 | 0.71 | CYP1A2 (0.38) | GLAKMT2AALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1485372-A2 | BICYCLIC FUSED PYRIDINYL AMIDES AND ADVANTAGEOUS COMPOSITIONS THEREOF FOR USE AS FUNGICIDES | E. I. du Pont de Nemours and Company (US) | 2004-12-15 | — | — | EP | claimed |
| WO-2003080596-A2 | BICYCLIC FUSED PYRIDINYL AMIDES AND ADVANTAGEOUS COMPOSITIONS THEREOF FOR USE AS FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-10-02 | — | — | WO | claimed |