Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.82 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 4/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267035 | 0.94 | CYP2C9 (0.90) | CYP2C9NR1I2MAPK1HSD17B10HIF1A | |
| SCHEMBL6234512 | 0.90 | CYP2C9 (1.00) | CYP2C9NR1I2MAPK1HSD17B10HIF1A | |
| SCHEMBL6736116 | 0.90 | CYP2C9 (0.84) | CYP2C9NR1I2MAPK1HSD17B10HIF1A | |
| SCHEMBL7075766 | 0.90 | CYP2C9 (0.73) | CYP2C9NR1I2MAPK1HSD17B10HIF1A | |
| SCHEMBL6692151 | 0.89 | CYP2C9 (0.67) | CYP2C9NR1I2MAPK1HSD17B10HIF1A | |
| SCHEMBL6681450 | 0.89 | CYP2C9 (0.66) | CYP2C9NR1I2MAPK1HSD17B10KDM4E | |
| SCHEMBL6738292 | 0.88 | CYP2C9 (0.65) | CYP2C9NR1I2MAPK1HSD17B10HIF1A | |
| SCHEMBL6239158 | 0.87 | CYP2C9 (0.63) | CYP2C9NR1I2MAPK1HSD17B10KDM4E | |
| SCHEMBL1522252 | 0.87 | CYP2C9 (0.63) | CYP2C9NR1I2MAPK1HSD17B10KDM4E | |
| SCHEMBL1522640 | 0.86 | CYP2C9 (0.61) | CYP2C9NR1I2MAPK1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004052312-A2 | ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-06-24 | — | — | WO | claimed |