Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | AGXT | P21549 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 6/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15865984 | 0.82 | AGXT (0.48) | IDO1AGXTL3MBTL1TDP1MAOB | |
| SCHEMBL17216170 | 0.81 | IDO1 (0.44) | IDO1AGXTL3MBTL1TDP1MAOB | |
| SCHEMBL17216913 | 0.81 | IDO1 (0.44) | IDO1AGXTL3MBTL1TDP1MAOB | |
| SCHEMBL10617880 | 0.80 | L3MBTL1 (0.53) | IDO1AGXTL3MBTL1TDP1MAOB | |
| SCHEMBL14006342 | 0.80 | L3MBTL1 (0.53) | IDO1AGXTL3MBTL1TDP1MAOB | |
| SCHEMBL2903742 | 0.79 | MAOB (0.42) | L3MBTL1TDP1MAOBKDM4ECYP1A2 | |
| SCHEMBL2903739 | 0.79 | MAOB (0.42) | L3MBTL1TDP1MAOBKDM4ECYP1A2 | |
| SCHEMBL17219621 | 0.79 | IDO1 (0.42) | IDO1AGXTL3MBTL1TDP1MAOB | |
| SCHEMBL211957 | 0.79 | NPC1 (0.46) | IDO1AGXTL3MBTL1TDP1ALDH1A1 | |
| SCHEMBL134049 | 0.79 | NPC1 (0.46) | IDO1AGXTL3MBTL1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004069145-A2 | ANTICANCER COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2004-08-19 | — | — | WO | claimed |