SCHEMBL2903739

SCHEMBL2903739

C/C=N/OCc1ccc(F)c(F)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.42
MAOA P21397 2/20 0.42
HTR6 P50406 2/20 0.36
ACHE P22303 1/20 0.36
CCR5 P51681 1/20 0.36
ALDH1A1 P00352 2/20 0.35
HTT P42858 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.33
DRD4 P21917 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
MAPT P10636 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
RIPK1 Q13546 1/20 0.32
KDM4E B2RXH2 2/20 0.32
CYP1A2 P05177 2/20 0.32
HPGD P15428 2/20 0.32
CYP2C19 P33261 2/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2903742 1.00 MAOB (0.42) MAOBMAOAHTR6ACHECCR5
SCHEMBL17215989 0.83 MAOB (0.40) MAOBMAOAHTR6ACHECCR5
SCHEMBL17215473 0.83 MAOB (0.40) MAOBMAOAHTR6ACHECCR5
SCHEMBL17218146 0.81 MAOB (0.39) MAOBMAOAHTR6ACHECCR5
SCHEMBL17219599 0.80 MAOB (0.38) MAOBMAOAHTR6ACHECCR5
SCHEMBL6684569 0.79 IDO1 (0.47) MAOBALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL17216579 0.78 MAOA (0.37) MAOBMAOAHTR6ACHECCR5
SCHEMBL14006342 0.76 L3MBTL1 (0.53) MAOBMAOAALDH1A1HTTL3MBTL1
SCHEMBL10617880 0.76 L3MBTL1 (0.53) MAOBMAOAALDH1A1HTTL3MBTL1
SCHEMBL31392780 0.76 MAOB (0.41) MAOBMAOAHTR6ACHECCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2010-11-11 US claimed
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2010-11-11 US disclosed
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2010-11-11 US disclosed
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286211-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS OXA1L, PDK4, MLYCD MAOB 2038/4885MAOA 1717/4885HTR6 4452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.