SCHEMBL6684707

SCHEMBL6684707

CCCCc1ccc(NC(=S)Nc2ccccc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.72
LMNA P02545 6/20 0.66
MAPT P10636 5/20 0.65
KMT2A Q03164 4/20 0.65
GAA P10253 4/20 0.65
ALOX12 P18054 3/20 0.65
SMN1; SMN2 Q16637 2/20 0.65
MEN1 O00255 1/20 0.65
HPGD P15428 1/20 0.65
MAPK1 P28482 1/20 0.65
L3MBTL1 Q9Y468 1/20 0.65
TRPV1 Q8NER1 1/20 0.63
HTT P42858 3/20 0.61
CYP1A2 P05177 1/20 0.59
CYP2D6 P10635 1/20 0.59
CYP2C9 P11712 1/20 0.59
CYP2C19 P33261 1/20 0.59
NPC1 O15118 1/20 0.57
RAB9A P51151 1/20 0.57
CYP3A4 P08684 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17956770 0.94 ALDH1A1 (0.64) ALDH1A1LMNAMAPTKMT2AGAA
SCHEMBL9469081 0.87 KMT2A (0.60) ALDH1A1LMNAMAPTKMT2AGAA
SCHEMBL9453932 0.86 LMNA (0.65) ALDH1A1LMNAMAPTKMT2AGAA
SCHEMBL9453903 0.86 LMNA (0.65) ALDH1A1LMNAMAPTKMT2AGAA
SCHEMBL15840672 0.85 ALDH1A1 (0.63) ALDH1A1LMNAMAPTKMT2ASMN1; SMN2
SCHEMBL4107205 0.83 TRPV1 (0.72) MAPTKMT2AGAASMN1; SMN2MEN1
SCHEMBL5445603 0.82 SMN1; SMN2 (0.73) ALDH1A1LMNAMAPTKMT2AGAA
SCHEMBL17637655 0.82 LMNA (0.58) ALDH1A1LMNAMAPTKMT2AGAA
SCHEMBL8868371 0.81 ALDH1A1 (0.63) ALDH1A1LMNAMAPTKMT2AGAA
SCHEMBL2539187 0.80 TRPV1 (0.58) ALDH1A1LMNAMAPTKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4599630-A USING LEUCO DYES WHICH FORM TWO DIFFERENT COLORS WHEN HEATED AT DIFFERENT TEMPERATURES RICOH COMPANY, LTD. (JP) 1986-07-08 US claimed
EP-3225737-A1 WOOD PULP FOR GLASS PLATE INTERLEAVING PAPER, AND GLASS PLATE INTERLEAVING PAPER Tokushu Tokai Paper Co., Ltd. (JP) 2017-10-04 EP disclosed
US-20040145562-A1 Electrophoretic display and process for producing the same CANON KABUSHIKI KAISHA (JP) 2004-07-29 US disclosed
WO-2004038497-A1 ELECTROPHORETIC DISPLAY AND PROCESS FOR PRODUCING THE SAME CANON KABUSHIKI KAISHA (JP) 2004-05-06 WO disclosed
EP-1149877-B1 Decolorizable ink composition and ink jet printer using the ink composition RICOH KK (JP) 2003-06-11 EP disclosed
US-6527384-B2 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2003-03-04 US disclosed
US-20020175982-A1 Decolorizable ink composition and ink jet printer using the ink composition RICOH COMPANY, LTD. (JP) 2002-11-28 US disclosed
EP-1149877-A1 Decolorizable ink composition and ink jet printer using the ink composition Ricoh Company, Ltd. (JP) 2001-10-31 EP disclosed
US-4755831-A Multi-layer full-color thermosensitive sheet recording method RICOH COMPANY, LTD. (JP) 1988-07-05 US disclosed
US-4665410-A THERMOGRAPHY RICOH COMPANY, LTD. (JP) 1987-05-12 US disclosed
US-4663641-A LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES RICOH COMPANY, LTD. (JP) 1987-05-05 US disclosed
US-4620204-A MILTILAYER-SUPPORT, HIGH TEMPERATURE THERMOSENSITIVE LAYER, VINYLIDENE CHLORIDE INTERMEDIATE LAYER AND LOW TEMPERATURE COLOR FORMING LAYER RICOH COMPANY, LTD. (JP) 1986-10-28 US disclosed
US-4613878-A DECOLORIZING AGENT COMPRISING AROMATIC DIAMIDE OR PIPERAZINE DERIVATIVE, HAVING TWO ACYLAMINO GROUPS RICOH COMPANY, LTD. (JP) 1986-09-23 US disclosed
US-4599630-A USING LEUCO DYES WHICH FORM TWO DIFFERENT COLORS WHEN HEATED AT DIFFERENT TEMPERATURES RICOH COMPANY, LTD. (JP) 1986-07-08 US disclosed