Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20891 | 0.74 | — | — | |
| Acetone SCHEMBL2143582 | 0.74 | LMNA (0.55) | TDP1ALDH1A1MAPTLMNA | |
| Acetone SCHEMBL28012321 | 0.71 | LMNA (0.50) | ALDH1A1MAPTLMNA | |
| SCHEMBL30581182 | 0.71 | — | — | |
| SCHEMBL1190178 | 0.71 | — | — | |
| SCHEMBL1925147 | 0.71 | ALDH1A1 (0.50) | TDP1ALDH1A1MAPTLMNA | |
| SCHEMBL1332099 | 0.71 | — | — | |
| SCHEMBL2415 | 0.71 | — | — | |
| SCHEMBL4820393 | 0.71 | — | — | |
| SCHEMBL30581185 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6818247-B1 | CAN INCLUDE AN ACTIVE AGENT SUCH AS ACTINOMYCIN D, PACLITAXEL, DOCETAXEL, OR RAPAMYCIN | ADVANCED CARDIOVASCULAR SYSTEMS, INC. | 2004-11-16 | — | — | US | disclosed |