Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3723028 | 0.94 | TGM2 (0.53) | TGM2CTSKPPARASMN1; SMN2PPARG | |
| SCHEMBL8142303 | 0.89 | CTSK (0.61) | TGM2CTSKSMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL3630687 | 0.89 | CTSK (0.61) | TGM2CTSKSMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL3659010 | 0.89 | CTSK (0.61) | TGM2CTSKSMN1; SMN2ITGB3ITGA2B | |
| SCHEMBL5181822 | 0.88 | ITGB1 (0.52) | PPARASMN1; SMN2PPARGITGB3ITGA2B | |
| SCHEMBL8023605 | 0.88 | ITGB1 (0.52) | PPARASMN1; SMN2PPARGITGB3ITGA2B | |
| SCHEMBL8305419 | 0.83 | PPARA (0.46) | PPARAPPARGMAPTALDH1A1LMNA | |
| SCHEMBL3719520 | 0.82 | CTSK (0.63) | TGM2CTSKSMN1; SMN2NPC1RAB9A | |
| SCHEMBL16465117 | 0.80 | CTSK (0.60) | CTSKSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5177894 | 0.80 | CTSK (0.48) | TGM2CTSKSMN1; SMN2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071448-A2 | SUBSTITUTED AZOLE DERIVATIVES AS INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | TRANSTECH PHARMA INC. (US) | 2004-08-26 | — | — | WO | disclosed |