SCHEMBL6684869

SCHEMBL6684869

BrC(Br)CCc1cccc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.48
CYP2C19 P33261 3/20 0.48
CYP2C9 P11712 2/20 0.48
CYP2D6 P10635 1/20 0.46
ALDH1A1 P00352 1/20 0.45
SLC18A2 Q05940 1/20 0.45
MTNR1A P48039 2/20 0.45
NQO2 P16083 1/20 0.45
TDP1 Q9NUW8 1/20 0.44
ACP3 P15309 1/20 0.43
SIGMAR1 Q99720 1/20 0.42
DAO P14920 1/20 0.41
CTNNB1 P35222 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6680540 0.89 SIGMAR1 (0.47) CYP1A2CYP2C19CYP2C9CYP2D6ALDH1A1
SCHEMBL6680566 0.87 SIGMAR1 (0.46) CYP1A2CYP2C19CYP2C9CYP2D6ALDH1A1
SCHEMBL6685433 0.85 SIGMAR1 (0.44) CYP1A2CYP2C19CYP2C9CYP2D6ALDH1A1
SCHEMBL6681397 0.85 SIGMAR1 (0.44) CYP1A2CYP2C19CYP2C9CYP2D6ALDH1A1
SCHEMBL6684260 0.85 SIGMAR1 (0.44) CYP1A2CYP2C19CYP2C9CYP2D6ALDH1A1
SCHEMBL6684964 0.85 TDP1 (0.46) CYP1A2CYP2C19CYP2C9CYP2D6ALDH1A1
SCHEMBL8375543 0.81 MTNR1A (0.46) CYP1A2CYP2C19CYP2C9CYP2D6SLC18A2
SCHEMBL7907492 0.81 NQO2 (0.50) CYP1A2CYP2C19CYP2C9CYP2D6SLC18A2
SCHEMBL3047898 0.80 CYP1A2 (0.62) CYP1A2CYP2C19CYP2C9CYP2D6ALDH1A1
SCHEMBL2875377 0.80 SLC6A2 (0.39) CYP1A2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed