Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL715892 | 0.86 | ALDH1A1 (0.42) | ALDH1A1MAPTKMT2APKMMEN1 | |
| SCHEMBL16492043 | 0.82 | ALDH1A1 (0.52) | ALDH1A1MAPTKMT2APKMMEN1 | |
| SCHEMBL8514106 | 0.79 | ALDH1A1 (0.37) | ALDH1A1MAPTKMT2APKMMEN1 | |
| SCHEMBL657504 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MAPTKMT2APKMMEN1 | |
| SCHEMBL29697575 | 0.79 | ALDH1A1 (0.52) | ALDH1A1MAPTKMT2APKMMEN1 | |
| SCHEMBL179803 | 0.78 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2APKMMEN1 | |
| SCHEMBL256203 | 0.78 | ALDH1A1 (0.64) | ALDH1A1MAPTKMT2APKMMEN1 | |
| SCHEMBL29377581 | 0.78 | ALDH1A1 (0.64) | ALDH1A1MAPTKMT2APKMMEN1 | |
| SCHEMBL29403104 | 0.78 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2APKMMEN1 | |
| SCHEMBL6759328 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPTKMT2APKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3675847-B1 | SPIROCYCLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H LUNDBECK AS (DK) | 2023-07-12 | — | — | EP | disclosed |
| WO-2014194254-A1 | TREATMENT OF CANCERS USING PI3 KINASE ISOFORM MODULATORS | INFINITY PHARMACEUTICALS, INC. (US) | 2014-12-04 | — | — | WO | disclosed |
| JP-2004210707-A | METHOD FOR PRODUCING 2-AMINO-4-t-BUTYLTHIOPHENOLS AND 2-ALKYLTHIO-5-t-BUTYLANILINES, AND COMPOUND OBTAINED BY THE PRODUCTION METHOD | FUJI PHOTO FILM CO LTD | 2004-07-29 | — | — | JP | disclosed |