Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 3/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29697575 | 1.00 | ALDH1A1 (0.52) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL29892011 | 0.98 | ALDH1A1 (0.50) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL444567 | 0.98 | ALDH1A1 (0.50) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL23411125 | 0.96 | ALDH1A1 (0.48) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL6759328 | 0.88 | ALDH1A1 (0.41) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL29464084 | 0.86 | ESR1 (0.41) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL295863 | 0.86 | ESR1 (0.41) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL16593687 | 0.85 | ALDH1A1 (0.39) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL25211449 | 0.81 | ALDH1A1 (0.37) | ALDH1A1KDM4EPKMHPGDHSD17B10 | |
| SCHEMBL2788945 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4EPKMHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4723010-A | Process for preparing chloromethyl thiazoles or oxazoles, and intermediates for use therein | PFIZER INC. (US) | 1988-02-02 | — | — | US | claimed |
| JP-3044383-A | — | — | None | — | — | JP | disclosed |
| CN-121824374-A | Preparation method and application of 2-amino-4-trifluoromethylthiophenol | 山东达因海洋生物制药股份有限公司 | 2026-04-10 | — | — | CN | disclosed |
| CN-121824374-A | Preparation method and application of 2-amino-4-trifluoromethylthiophenol | 山东达因海洋生物制药股份有限公司 | 2026-04-10 | — | — | CN | disclosed |
| WO-2025125829-A1 | NORA INHIBITORS | IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) | 2025-06-19 | — | — | WO | disclosed |
| US-20250129063-A1 | BENZOTHIAZOLE COMPOUNDS AS VHL LIGANDS | GENENTECH, INC. (US) | 2025-04-24 | — | — | US | disclosed |
| WO-2025071094-A1 | USES OF MERCAPTO FUNCTIONAL COMPOUND HAVING TYROSINASE INHIBITORY ACTIVITY | 부산대학교 산학협력단 | 2025-04-03 | — | — | WO | disclosed |
| US-20240262832-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2024-08-08 | — | — | US | disclosed |
| CN-118084897-A | Iron ion detection reagent and preparation method and application thereof | 河南省氟基新材料科技有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-117715907-A | 10-substituted-1-azaphenothiazine derivative and application thereof | 华东理工大学 | 2024-03-15 | — | — | CN | disclosed |
| EP-0295051-B1 | PREPARATION OF OXOPHTHALAZINYL ACETIC ACIDS HAVING BENZOTHIAZOLE OR OTHER HETEROCYCLIC SIDE CHAINS | PFIZER INC. (US) | 1993-06-09 | — | — | EP | disclosed |
| WO-1992019277-A1 | ANTIVIRAL DIBENZOTHIAZEPINONE DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-11-12 | — | — | WO | disclosed |
| WO-1992019607-A1 | DIBENZOTHIAZEPINTHIONE AS ANTIVIRAL AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-11-12 | — | — | WO | disclosed |
| WO-1992012161-A1 | NOVEL PYRIMIDO-BENZOTHIAZINES | PFIZER INC. (US) | 1992-07-23 | — | — | WO | disclosed |
| EP-0222576-B1 | HETEROCYCLIC OXOPHTHALAZINYL ACETIC ACIDS | PFIZER INC. (US) | 1992-03-18 | — | — | EP | disclosed |
| JP-H0344383-A | PRODUCTION OF 5-TRIFLUOROMETHYL-2-HALOMETHYLBENZOTHIAZOLES | IHARA CHEM IND CO LTD | 1991-02-26 | — | — | JP | disclosed |
| US-4748280-A | Certain chlorination process for preparing 2-chloro-1,1,1-(C1 -C6) | PFIZER INC. (US) | 1988-05-31 | — | — | US | disclosed |
| US-4723010-A | Process for preparing chloromethyl thiazoles or oxazoles, and intermediates for use therein | PFIZER INC. (US) | 1988-02-02 | — | — | US | disclosed |
| EP-0222576-A2 | Heterocyclic oxophthalazinyl acetic acids | PFIZER INC. (US) | 1987-05-20 | — | — | EP | disclosed |
| US-3984405-A | PYRIDO(3,2-B)(1,4)OXAZIN-3(4H)-ONES | E. R. SQUIBB & SONS, INC. (US) | 1976-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129063-A1 | BENZOTHIAZOLE COMPOUNDS AS VHL LIGANDS | VHL, BRCA1, GLS | ALDH1A1 2210/4885KDM4E 1366/4885PKM 1044/4885 |
| US-20240262832-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | GBA1, GAA, GBA2 | ALDH1A1 1938/4885KDM4E 3762/4885PKM 1040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.