Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 16/20 | 0.55 |
| ▸ | CTSL | P07711 | 11/20 | 0.55 |
| ▸ | CTSK | P43235 | 10/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5499131 | 0.84 | CTSS (0.57) | CTSSCTSLCTSKALDH1A1SMN1; SMN2 | |
| SCHEMBL6690368 | 0.81 | CTSS (0.58) | CTSSCTSLCTSKALDH1A1 | |
| SCHEMBL6690397 | 0.79 | CTSS (0.54) | CTSSCTSLCTSK | |
| SCHEMBL6687985 | 0.78 | CTSS (0.56) | CTSSCTSLCTSK | |
| SCHEMBL6693346 | 0.78 | CTSS (0.69) | CTSSCTSLCTSK | |
| SCHEMBL6690165 | 0.78 | CTSS (0.54) | CTSSCTSLCTSKALDH1A1 | |
| SCHEMBL6689691 | 0.78 | CTSS (0.56) | CTSSCTSLCTSK | |
| SCHEMBL3019568 | 0.78 | CTSS (0.62) | CTSSCTSLCTSK | |
| SCHEMBL5841446 | 0.78 | CTSS (0.62) | CTSSCTSLCTSK | |
| SCHEMBL6688293 | 0.78 | CTSS (0.57) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084842-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |