SCHEMBL6685291

SCHEMBL6685291

CCC(C(=O)OC(=O)CN)C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5168491 0.76
SCHEMBL27802394 0.75 CA2 (0.36) CA1CA2CYP1A2
SCHEMBL1252195 0.74 CYP1A2 (0.33) CYP1A2
SCHEMBL28179517 0.73 CA1 (0.32) CA1CA2
SCHEMBL17617125 0.73 ALDH1A1 (0.42) CA1CA2CA7CA14CYP1A2
SCHEMBL13690831 0.73 CA1 (0.47) CA1CA2CA7CA14
SCHEMBL1275780 0.73 TSHR (0.35) CA1CA2CA7CA14
SCHEMBL17617121 0.73 ALDH1A1 (0.42) CA1CA2CA7CA14CYP1A2
SCHEMBL17617142 0.73 ALDH1A1 (0.42) CA1CA2CA7CA14CYP1A2
SCHEMBL6238166 0.71 TSHR (0.33) CA1CA2CA7CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004074316-A1 CONFORMATIONALLY CONSTRAINED BACKBONE CYCLIZED PEPTIDE ANALOGS GILON CHAIM (IL) 2004-09-02 WO disclosed
EP-0804468-A1 CONFORMATIONALLY CONSTRAINED BACKBONE CYCLIZED PEPTIDE ANALOG PEPTOR LTD (IL) 1997-11-05 EP disclosed
WO-1995033765-A1 CONFORMATIONALLY CONSTRAINED BACKBONE CYCLIZED PEPTIDE ANALOG PEPTOR LTD. (IL) 1995-12-14 WO disclosed