SCHEMBL6685306

SCHEMBL6685306

CCCCCCC(Br)(Br)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.41
EBP Q15125 1/20 0.41
GAA P10253 1/20 0.39
DNM1 Q05193 2/20 0.39
SCN5A Q14524 3/20 0.39
SCN9A Q15858 3/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
CNR2 P34972 2/20 0.38
TP53 P04637 1/20 0.38
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
EPHX2 P34913 1/20 0.38
PKM P14618 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
CNR1 P21554 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22320089 1.00 SIGMAR1 (0.41) SIGMAR1EBPGAADNM1SCN5A
SCHEMBL6686630 1.00 SIGMAR1 (0.41) SIGMAR1EBPGAADNM1SCN5A
SCHEMBL6689783 0.98 SIGMAR1 (0.41) SIGMAR1EBPGAADNM1SCN5A
SCHEMBL6686318 0.91 KIF11 (0.41) SIGMAR1MEN1KMT2A
SCHEMBL31376077 0.85 SIGMAR1 (0.42) SIGMAR1EBPGAADNM1SCN5A
SCHEMBL9440826 0.83 KIF11 (0.39) SIGMAR1SMN1; SMN2
SCHEMBL6682083 0.82 KCNN4 (0.43) SIGMAR1TP53MAPK1SMN1; SMN2
SCHEMBL21577161 0.82 SIGMAR1 (0.40) SIGMAR1EBPGAADNM1SCN5A
SCHEMBL28255218 0.82 SIGMAR1 (0.40) SIGMAR1EBPGAADNM1SCN5A
SCHEMBL1581587 0.82 SIGMAR1 (0.40) SIGMAR1EBPGAADNM1SCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed