Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11650412 | 0.86 | LMNA (0.46) | LMNAALDH1A1HSD17B10NR1I2CYP1A2 | |
| SCHEMBL11650649 | 0.86 | LMNA (0.46) | LMNAALDH1A1HSD17B10NR1I2CYP1A2 | |
| SCHEMBL11653036 | 0.82 | — | — | |
| SCHEMBL3075615 | 0.79 | — | — | |
| SCHEMBL20271865 | 0.79 | — | — | |
| SCHEMBL331090 | 0.75 | — | — | |
| SCHEMBL29159578 | 0.73 | NR1I2 (0.42) | LMNAALDH1A1HSD17B10NR1I2CYP1A2 | |
| SCHEMBL24071271 | 0.73 | LMNA (0.32) | LMNAALDH1A1HSD17B10NR1I2CYP1A2 | |
| SCHEMBL24071237 | 0.73 | LMNA (0.32) | LMNAALDH1A1HSD17B10NR1I2CYP1A2 | |
| SCHEMBL25218772 | 0.71 | GSTK1 (0.52) | LMNAALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392760-B1 | PHOTOPOLYMERIZATION OF EPISULFIDES USING METAL COMPLEXES AND ITS USE FOR MAKING OPHTHALMIC LENSES | ESSILOR INT (FR) | 2004-10-13 | — | — | EP | disclosed |