Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 15/20 | 0.51 |
| ▸ | CTSK | P43235 | 9/20 | 0.51 |
| ▸ | CTSL | P07711 | 8/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686940 | 0.91 | CTSS (0.56) | CTSSCTSKCTSLFAAHEPHX2 | |
| SCHEMBL6693646 | 0.90 | CTSS (0.61) | CTSSCTSKCTSL | |
| SCHEMBL6685630 | 0.86 | NPC1 (0.51) | CTSSCTSKCTSLEPHX2 | |
| SCHEMBL6689357 | 0.85 | CTSS (0.50) | CTSSCTSKCTSLFAAHEPHX2 | |
| SCHEMBL6690062 | 0.83 | CTSS (0.48) | CTSSCTSKCTSLEPHX2 | |
| SCHEMBL5843010 | 0.83 | CTSS (0.71) | CTSSCTSKCTSL | |
| SCHEMBL5843004 | 0.83 | CTSS (0.71) | CTSSCTSKCTSL | |
| SCHEMBL6689172 | 0.83 | CTSS (0.61) | CTSSCTSKCTSL | |
| SCHEMBL6691227 | 0.80 | CTSS (0.48) | CTSSCTSKCTSLEPHX2 | |
| SCHEMBL6693346 | 0.80 | CTSS (0.69) | CTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084842-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |