Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.71 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.60 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.60 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.60 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685672 | 1.00 | ADORA3 (0.71) | ADORA3ADORA1ADORA2AADORA2BTSHR | |
| SCHEMBL6673454 | 0.95 | ADORA3 (0.73) | ADORA3ADORA1ADORA2AADORA2BTSHR | |
| SCHEMBL6671330 | 0.90 | ADORA1 (0.71) | ADORA3ADORA1ADORA2AADORA2BPMP22 | |
| SCHEMBL6670776 | 0.87 | ADORA3 (0.68) | ADORA3ADORA1ADORA2AADORA2BTAS1R3 | |
| SCHEMBL6670771 | 0.87 | ADORA3 (0.68) | ADORA3ADORA1ADORA2AADORA2BTAS1R3 | |
| SCHEMBL6672392 | 0.85 | ADORA3 (0.61) | ADORA3ADORA1ADORA2AADORA2BTSHR | |
| SCHEMBL6256839 | 0.84 | ADORA3 (0.59) | ADORA3ADORA1ADORA2AADORA2BTSHR | |
| SCHEMBL6262038 | 0.84 | ADORA3 (0.59) | ADORA3ADORA1ADORA2AADORA2BTSHR | |
| SCHEMBL6670773 | 0.84 | ADORA3 (0.73) | ADORA3ADORA1ADORA2AADORA2BTSHR | |
| SCHEMBL14906549 | 0.81 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AADORA2BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026890-A1 | ACETYLENE COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2004-04-01 | — | — | WO | claimed |